diff --git a/src/coreclr/jit/utils.cpp b/src/coreclr/jit/utils.cpp
index 3f3b49dc55b933..86300e47383b0f 100644
--- a/src/coreclr/jit/utils.cpp
+++ b/src/coreclr/jit/utils.cpp
@@ -1596,9 +1596,12 @@ void HelperCallProperties::init()
                 break;
 
             // GETREFANY is pure up to the value of the struct argument. We
-            // only support that when it is not an implicit byref.
+            // only support that when it is not an implicit byref. The
+            // TypedReference struct (two pointers) is passed by implicit
+            // byref on win-x64 and on wasm (the wasm ABI passes any struct
+            // without a single scalar lowering by reference).
             case CORINFO_HELP_GETREFANY:
-#ifndef WINDOWS_AMD64_ABI
+#if !defined(WINDOWS_AMD64_ABI) && !defined(TARGET_WASM)
                 isPure = true;
 #endif
                 break;